Systematic review and meta-analysis on "Safety of premedication in reducing pain/stress in neonates undergoing non-urgent endotracheal intubation"

It is required to do a systematic review and meta-analysis to "Assess the effectiveness and safety of premedication in reducing pain/stress in neonates undergoing non-urgent endotracheal intubation". Only randomised controlled trials (RCTs), quasi-RCTs, cluster-RCTs and randomised cross-over trials should be included. Databases to be searched are Cochrane Central Register of Controlled Trials (CENTRAL, current issue) in the Cochrane Library; MEDLINE via PubMed (1966 to current); Embase (1980 to current); and CINAHL (1982 to current). I will provide the detailed search strategy and keywords to conduct the search. Collect as many published literature on the topic as possible, then screen them following the PRISMA guidleines and inclusion/exclusion criteria. Then perform meta-analysis on the qualified studies to determine teh forest plot to draw meaningful inferences. Based on the meta-analysis result, it is required to write a full paper of about 3000 words (words in references are not counted) on "Premedication for non-urgent endotracheal intubation for preventing pain in neonates".