Tunnel build TIMMEDOUT (with ip rule and local tunnel)

I need someone to correct my tunnel between two machine on Linux DEBIAN to communicate (send email). When I try to send data to the distant remote server I have TIMEDOUT error. I have build my tunnel like this, with special IP rule to push back traffic but it still don't works. I used this command as exemple to give you an idea : ip tunnel add mytun1 mode gre local [login to view URL] remote [login to view URL] ttl 255 ip link set mytun1 up ip address add [login to view URL] dev mytun1 ip rule add from [login to view URL] lookup 50 ip route add default dev mytun1 table 50 ifconfig eth0:1 [login to view URL] netmask [login to view URL] up nc -s [login to view URL] [login to view URL] 25 220 [login to view URL] ESMTP dg1si3391722pbd.139 - gsmtp TIMMEDOUT